Can people with nodular panniculitis receive vaccines?
Dec 12, 2025
Source: Cainiu Health
Dr. Li Feng
Introduction
In general, whether patients with nodular panniculitis can receive vaccines depends on the activity status of their condition. Vaccination is usually acceptable during stable phases, but not recommended during acute flare-ups. To ensure vaccination safety, it is essential to clarify the disease status before vaccination and inform the healthcare provider of personal medical history and current medications in advance. After vaccination, close observation is necessary, and routine skin care should be maintained.
In general, whether patients with nodular panniculitis can receive vaccines depends on the activity status of their condition. Vaccination is usually acceptable during stable phases, but not recommended during acute flare-ups. The specific analysis is as follows:
If the patient is in a stable phase—skin nodules and pain are under control, there is no significant inflammatory response, and there are no other contraindications to vaccination—vaccination is feasible. In such cases, vaccination will not exacerbate the existing condition and can provide the intended protective benefits.
If the patient is experiencing an acute flare-up, characterized by increasing skin nodules, worsening pain, or associated symptoms such as fever and fatigue, the body is in an active inflammatory state. Vaccination in this situation may increase the risk of adverse reactions and could interfere with the assessment of disease progression; therefore, it is not recommended.
To ensure vaccination safety, patients should confirm their current disease status before vaccination and inform healthcare providers of their medical history and medication use. After vaccination, they should remain under observation, maintain proper skin care in daily life, avoid irritating affected areas, and continue regular medication to keep the condition stable.
