Does teratozoospermia significantly affect the success rate of IVF?
Apr 02, 2022
Source: Cainiu Health
Dr. Wang Jianlong
Introduction
Long-term unhealthy lifestyle habits—such as smoking and excessive alcohol consumption—have been shown in studies to elevate blood levels of alcohol and nicotine, leading to increased sperm morphological abnormalities and significantly reduced sperm motility. Endocrine disorders can also cause sperm deformities; in some patients, these disorders directly result in insufficient secretion of certain hormones. During spermatogenesis in the seminiferous tubules, endocrine imbalances and hormonal deficiencies further increase the rate of sperm morphological abnormalities.
Every family hopes for a healthy and intelligent baby. However, due to various factors, many couples experience infertility or subfertility, prompting them to consider in vitro fertilization (IVF) to fulfill their dream of parenthood. But how successful is IVF for men diagnosed with teratozoospermia (abnormal sperm morphology)?
Is IVF Success Rate High for Men with Teratozoospermia?
If routine semen analysis reveals a high percentage of morphologically abnormal sperm, this may increase the risk of intrauterine miscarriage or fetal malformations. It is recommended that affected men undergo treatment—such as oral administration of traditional Chinese herbal formulas (e.g., Sheng Jing Tang) or proprietary medicines (e.g., Sheng Jing Pian)—to improve sperm morphology. Additionally, adopting healthier lifestyle habits—including reducing smoking, limiting alcohol consumption, and avoiding late-night sleep—is essential. Once sperm quality and overall health have normalized, couples may proceed with conception planning.
Long-term unhealthy habits—such as smoking and excessive alcohol intake—have been shown in studies to elevate blood levels of nicotine and alcohol, leading to increased sperm abnormalities and significantly reduced sperm motility. Hormonal imbalances can also cause teratozoospermia; in some cases, these imbalances directly result from insufficient secretion of certain hormones. During spermatogenesis in the seminiferous tubules, endocrine dysregulation and hormonal deficiencies may further elevate the incidence of abnormal sperm morphology. Urogenital infections—including common conditions such as prostatitis and epididymo-orchitis—can alter the physical and chemical properties of semen, elevating harmful substances that contribute to sperm abnormalities. In patients with varicocele, elevated local testicular temperature impairs normal sperm development, resulting in immature sperm and structural abnormalities.
Maintain regular, healthy daily routines. We hope this information has been helpful to you.
