Is plague contagious?
Skin infections and gastrointestinal infections are also among the most common transmission routes. So, is plague contagious?
Is Plague Contagious?
Plague is a highly infectious disease primarily transmitted by fleas. It is a naturally occurring zoonotic disease prevalent among wild rodents. Clinically, it manifests mainly as high fever, lymphadenopathy, hemorrhagic tendencies, and pulmonary inflammation. Plague is extremely contagious; without treatment, its fatality rate can reach 30%–60%. It is classified as both an internationally quarantinable disease and a Category A notifiable infectious disease under Chinese law. Historically, plague has caused devastating pandemics with high mortality—most notably the “Black Death” in 14th-century Europe, which claimed approximately 50 million lives. Plague is a naturally occurring zoonotic disease, with endemic foci distributed across more than 60 countries and regions in Asia, Africa, the Americas, and elsewhere. The primary reservoirs are rodents, including rats and guinea pigs.

Gastrointestinal infection is one of the most common modes of plague transmission. The black rat (*Rattus rattus*) and brown rat (*Rattus norvegicus*) are the most important reservoirs; indeed, any rodent species may serve as a potential source of infection. Among the clinical forms, pneumonic plague poses the greatest threat to human health, while septicemic plague exhibits the highest level of bacteremia during its early stage. Therefore, individuals are advised to avoid consuming rodent-derived foodstuffs in daily life. Additionally, certain wild animals may carry pathogenic organisms; thus, contact with or consumption of such animals should be avoided whenever possible.

Consequently, failure to implement timely control measures and isolation for confirmed cases may readily lead to plague outbreaks. Wishing you good health and a joyful life!