What are the transmission routes of plague?
Plague is a zoonotic disease with natural foci, and it can be transmitted through multiple routes. So, what are the transmission routes of plague?
What Are the Transmission Routes of Plague?
Plague has several transmission routes, primarily including: contact transmission, such as capturing, slaughtering, skinning, or consuming infected animals—directly or indirectly contacting plague-infected animals. Bacteria may enter the human body through wounds on the hands, subsequently spreading via lymphatic vessels or the bloodstream to cause bubonic or septicemic plague. Even minute skin injuries—such as hangnails—can serve as entry points for infection.

Airborne transmission: Infected individuals exhale large quantities of air containing plague bacilli. When patients breathe, cough, or sneeze, they release Yersinia pestis into the surrounding air, forming infectious bacterial particles and aerosols. These airborne suspensions readily infect others, potentially triggering outbreaks of human pneumonic plague. Direct respiratory infection may also occur upon contact with pneumonically infected animals—such as dogs or cats infected with plague—leading to primary pneumonic plague.

Once plague infection progresses to pneumonic plague in humans, the disease becomes contagious even in its early stages. Human-to-human transmission of pneumonic plague can result in widespread epidemics, extending far beyond the original endemic area. In daily life, avoid close contact with animals; if accidental contact occurs, wash your hands promptly. We hope this information is helpful to you!