What are the clinical manifestations of uterine septum?
Jun 01, 2022
Source: Cainiu Health
Dr. Chong Yiwen
Introduction
Clinical manifestations of uterine septum include:
- Recurrent miscarriage, most commonly associated with congenital uterine anomalies, among which uterine septum is the most prevalent. The incidence of uterine septum is notably high in women experiencing recurrent pregnancy loss—particularly early pregnancy loss.
- Ectopic pregnancy.
- Increased risk of complications in late pregnancy.
- Menstrual disorders, such as significantly increased menstrual flow and prolonged menstrual duration.
Uterine septum is commonly caused by impaired fusion of the paired paramesonephric (Müllerian) ducts during embryonic development.
Clinical manifestations include:
① Recurrent miscarriage
Recurrent miscarriage is frequently associated with uterine malformations, among which uterine septum is the most common. The prevalence of uterine septum is notably high among women experiencing recurrent pregnancy loss—particularly early pregnancy loss.
② Ectopic pregnancy
Due to the complexity of uterine anomalies, ectopic pregnancies may occur in atypical locations such as an occluded uterine horn, a rudimentary uterine horn, the cervix, or vaginal diverticula. Because these sites are rare, pregnancies occurring in such unusual locations are often difficult to diagnose early.
③ Abnormal labor and delivery
The presence of a uterine septum causes uterine cavity distortion, thereby increasing the risk of complications in late pregnancy. Uterine malformations may also lead to obstetric complications including abnormal fetal presentation, dysfunctional uterine contractions, and retained placenta.
④ Menstrual disorders
In patients with a large uterine septum, menstrual flow is significantly increased, menses duration is prolonged, and irregular vaginal bleeding may occur.
