What does alanine aminotransferase (ALT) mean?

Hello, Alanine aminotransferase (ALT) is a normally occurring active enzyme located on the surface of hepatocyte membranes. Under normal liver conditions, ALT levels in the blood are typically low and often barely detectable. However, when hepatocyte membranes are damaged, large amounts of ALT are released into the bloodstream, leading to a marked elevation in serum ALT levels. ALT serves as a sensitive indicator of hepatic inflammation and reflects hepatocellular injury. Elevated ALT levels can occur in virtually all types of hepatitis. Management and treatment should therefore focus on identifying and addressing the underlying cause—such as eliminating the etiological factor—while also incorporating hepatoprotective measures and ALT-lowering therapies. We hope this information is helpful to you. Wishing you a happy and healthy life!