Clinical Manifestations of Ebola Hemorrhagic Fever
Disease description:
After returning from an overseas trip, I felt completely exhausted and developed a fever. My husband suspects I may have contracted Ebola. What are the clinical manifestations of Ebola virus disease?
The incubation period for Ebola hemorrhagic fever ranges from 2 to 21 days. Patients present acutely with fever, which rapidly progresses to high-grade fever, accompanied by fatigue, headache, myalgia, and sore throat. Nausea, vomiting, abdominal pain, diarrhea, and rash may also occur. By days 3–4 of illness, patients may enter the critical phase, characterized by persistent high fever, worsening septic-toxic symptoms and gastrointestinal manifestations, and varying degrees of hemorrhage—including mucocutaneous bleeding, hematemesis, hemoptysis, melena, and hematuria. Severe cases may develop altered mental status, shock, and multiorgan involvement; death typically occurs within two weeks of symptom onset, commonly due to hemorrhage and/or multiorgan failure.