What does it mean when AST, ALT, and total cholesterol are elevated?

Jun 04, 2024 Source: Cainiu Health
Disease description:

Sometimes I experience indigestion. After medical tests, I found my transaminase and cholesterol levels to be abnormal. I really want to know—what does it mean when AST, ALT, and total cholesterol are all elevated?

Doctor's answer (1)
Dr. Gao Jun

Elevated levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), along with high total cholesterol, are usually associated with various health issues.

1. Increased AST and ALT levels may indicate liver cell damage, which could be related to unhealthy lifestyle habits (such as excessive alcohol consumption, staying up late), fatty liver disease, viral hepatitis, cholecystitis, cirrhosis, and other conditions.

2. High total cholesterol reflects abnormal cholesterol metabolism in the body, possibly caused by factors such as a high-fat diet, excessive stress, lack of physical activity, hypothyroidism, or diabetes.

3. When these indicators are abnormal, further examinations are recommended to determine the specific causes, and appropriate treatments should be initiated. At the same time, improving lifestyle habits is essential for maintaining liver and cardiovascular health.