Is pediatric epilepsy inherited?

Jun 18, 2024 Source: Cainiu Health
Disease description:

Two months ago, my cousin's child was diagnosed with pediatric epilepsy and has been undergoing drug treatment. I would like to know whether pediatric epilepsy is inherited.

Doctor's answer (1)
Dr. Zhou Xiaofeng
Whether childhood epilepsy is inherited depends on its specific underlying cause. The probability of genetic inheritance in childhood epilepsy is approximately 10%–20%. Specifically: 1. Genetic factors: If one or both parents have epilepsy, or if there is a family history of epilepsy, the child's risk of developing epilepsy increases. This may be related to autosomal dominant inheritance or X-linked recessive inheritance. 2. Non-genetic factors: Not all cases of childhood epilepsy are due to genetic causes. Epilepsy can also result from structural brain abnormalities, brain injuries (such as birth trauma, head injury, or infections), metabolic disorders (such as hypoglycemia or vitamin B₆ deficiency), and other environmental factors (such as drug toxicity or toxic encephalopathy). For children suspected of having epilepsy, a comprehensive evaluation and diagnosis should be conducted, taking into account both genetic and non-genetic factors.