The most serious side effect of Aztreonam

The most serious adverse effects of aztreonam include central nervous system toxicity, anaphylactic shock, and immune reconstitution inflammatory syndrome. Central nervous system toxicity may lead to headache, dizziness, coma, and even death; anaphylactic shock presents as acute circulatory failure, such as palpitations, dyspnea, hypotension, and requires immediate resuscitation; immune reconstitution inflammatory syndrome may cause fever, rash, arthralgia, and similar symptoms. Additionally, drug-induced liver injury and loss of taste sensation are also considered severe adverse effects of aztreonam; the former may result in symptoms such as fatigue, nausea, and abdominal pain, while the latter affects the patient's sense of taste. Therefore, close monitoring of patient responses is essential during aztreonam therapy, and the medication should be used in accordance with medical instructions.