What is the maximum recommended interval between the first and second doses of the pediatric hand, foot, and mouth disease vaccine?

Jun 25, 2024 Source: Cainiu Health
Disease description:

My daughter is 6 years old this year. She suddenly developed many small pimples on her back, and the doctor confirmed it as hand, foot, and mouth disease. She has already received the first dose of the vaccine. I would like to know the maximum interval allowed for the second dose of the hand, foot, and mouth disease vaccine.

Doctor's answer (1)
Dr. Zhou Xiaofeng
The timing of the second dose of the pediatric hand, foot, and mouth disease (HFMD) vaccine is very important to ensure its effectiveness. Generally, the second dose should be administered one month after the first dose, and no later than six weeks afterward. This is because the HFMD vaccine requires two doses to generate sufficient immunity, with the main function of the second dose being to enhance the immune response. If the second dose is delayed beyond six weeks, it may affect the protective efficacy of the vaccine, as the child's immune system might mount a weaker response. Additionally, HFMD commonly affects children under five years of age and is highly contagious. Therefore, parents are advised to vaccinate their children promptly within the appropriate age range to prevent HFMD infection.