Can macrophage activation syndrome be cured?
Disease description:
Because my grandmother and father suffered from rheumatism, my daughter has inherited the condition, and it has now developed into severe complications, along with a series of symptoms including rashes and enlarged lymph nodes. According to the doctor, this disease has a high mortality rate. I am very worried about my daughter. I would like to ask the experts here whether this macrophage activation syndrome is curable?
Doctor's answer (1)
Dr. Liu Feng
Macrophage activation syndrome (also known as hemophagocytic syndrome) is generally difficult to cure, but symptoms can be relieved through treatment.
1. Treatment: The main treatment methods include the use of glucocorticoid medications (such as prednisone acetate tablets, methylprednisolone tablets), and immunosuppressive agents (such as compound cyclophosphamide tablets, azathioprine tablets). In severe cases, treatments such as plasma exchange and leukapheresis may be required.
2. Prognosis: Primary hemophagocytic syndrome usually requires allogeneic bone marrow transplantation for a cure, as it is very difficult to cure with chemotherapy alone. Secondary hemophagocytic syndrome requires first controlling the underlying disease, such as malignancy or severe infection, to relieve symptoms of hemophagocytic syndrome.
