Is a nephrectomy still necessary for kidney cancer that has already metastasized?

For renal cancer that has already metastasized, the decision to perform nephrectomy depends on a comprehensive evaluation of multiple factors. 1. Surgical outcomes: If the metastatic lesion is solitary and located in a surgically accessible area, nephrectomy combined with resection of the metastasis can significantly improve patient survival and cure rates. For example, in patients with renal cancer and isolated lung metastases, five-year survival rates can reach 25%–35% after lobectomy or segmental resection of the lung. 2. Comprehensive treatment: Following surgical removal, combined treatment strategies such as immunotherapy, radiation therapy, chemotherapy, or targeted drug therapy can further reduce the risk of recurrence and metastasis, thereby prolonging patient survival. 3. Patient status: The patient's overall health condition, age, and severity of illness also influence the decision for surgery. When selecting a treatment plan, patients should fully communicate and consult with specialized physicians to develop an individualized treatment strategy.