What does a high level of gamma-glutamyl transferase indicate?

Jun 29, 2024 Source: Cainiu Health
Disease description:

I usually feel that my physical condition is quite good. However, I enjoy drinking alcohol and don't smoke much. Recently, during a company-wide medical examination, my report showed elevated levels of gamma-glutamyl transferase (GGT). I would like to know what this indicates?

Doctor's answer (1)
Dr. Yang Ziqi
Elevated gamma-glutamyl transferase (GGT) levels usually indicate possible liver dysfunction or the presence of certain disease conditions. Elevated GGT levels may be caused by the following factors: 1. Physiological causes: For example, long-term alcohol consumption, vigorous exercise, improper diet (such as long-term high-protein intake), or significant mental stress, all of which may lead to increased GGT levels. 2. Pathological causes: Liver diseases such as viral hepatitis, fatty liver disease, and cirrhosis, as well as biliary tract diseases (such as biliary obstruction and cholecystitis), may all potentially cause a significant increase in GGT levels. 3. Medication effects: Long-term use of certain medications, such as sedatives and drugs for diabetes treatment, may also lead to elevated GGT levels. When elevated GGT levels are detected, timely medical consultation is necessary. A physician will evaluate the underlying cause and provide appropriate treatment based on the individual patient's condition.