How to Determine Coagulation Dysfunction in Hemophilia

The assessment of coagulation function in hemophilia mainly involves the following methods: 1. Clinical symptom observation: Observe whether the patient exhibits typical symptoms of hemophilia, such as prolonged bleeding after minor trauma or small surgeries, extensive skin bruising, deep muscle hematomas, and joint lesions. 2. Laboratory tests: Perform blood routine tests, coagulation time, activated partial thromboplastin time (aPTT), and prothrombin time (PT) measurements. Typically, patients with hemophilia will show prolonged coagulation time and prolonged activated partial thromboplastin time. 3. Specialized tests: Such as the prothrombin generation test and correction tests, which are crucial for confirming the diagnosis and classification of hemophilia. Based on the test results, it can be determined whether the condition is hemophilia A, hemophilia B, or factor XI deficiency.