Causes of Skin Itching in Liver Cirrhosis

The main causes of pruritus (itching) in cirrhosis include: 1. **Bile stasis**: Cirrhosis may damage bile ducts, leading to bile duct narrowing and impaired bile secretion, resulting in bile stasis. Bile acids can irritate the skin and cause itching, often accompanied by symptoms such as abdominal pain, bloating, and loss of appetite. 2. **Bilirubin metabolism disorder**: Liver dysfunction in cirrhosis affects bilirubin synthesis and excretion, leading to pruritus. Scratching may leave noticeable marks and is often accompanied by jaundice. 3. **Skin infection**: Patients with cirrhosis often have prolonged illness, significant physical debilitation, and weakened immunity. Minor skin injuries may lead to bacterial infections, causing pruritus and inflammatory skin manifestations. 4. **Eczema and skin allergy**: Some patients may develop eczema or be exposed to allergens, leading to symptoms such as skin itching, redness, and swelling. 5. **Other factors**: Hormonal changes, malnutrition, deficiency of trace elements, and neurological abnormalities may also contribute to pruritus in patients with cirrhosis.