Tuberculous Pleural Effusion Causes

Jul 08, 2024 Source: Cainiu Health
Disease description:

My family member has suddenly developed tuberculous pleural effusion, with symptoms of dry cough and difficulty breathing. May I ask, what are the causes of tuberculous pleural effusion?

Doctor's answer (1)
Dr. Yang Ziqi
Tuberculous pulmonary effusion, or pleural effusion, fundamentally results from infection by Mycobacterium tuberculosis. When this bacterium invades the pulmonary mucosa, it triggers a strong inflammatory response, leading to the production of large amounts of inflammatory secretions containing Mycobacterium tuberculosis, shed tissue fragments, and inflammatory metabolic products. These secretions progressively accumulate within the lungs, eventually forming pulmonary effusion, known as pleural effusion. Additionally, the patient's intense systemic response to the infection may also produce reactive effusion, further exacerbating the formation of pulmonary effusion. The occurrence of tuberculous pulmonary effusion often indicates a relatively severe condition requiring prompt and active treatment. Early, systematic, and standardized anti-tuberculosis therapy, combined with necessary thoracentesis for drainage of pleural fluid and corticosteroid treatment, can effectively control the disease progression and reduce the occurrence of pleural adhesion and post-treatment chest pain. During treatment, regular monitoring of liver function and enhanced nutritional support are also crucial components in promoting recovery.