What causes high prolactin levels?

Jul 12, 2024 Source: Cainiu Health
Disease description:

I am 28 years old. Recently, my menstrual cycle has become very irregular. Sometimes my period doesn't come for a long time, and even when it does, the flow is very light. I went to the hospital for a checkup, and the doctor told me that my prolactin level is high. I would like to ask, what causes elevated prolactin levels?

Doctor's answer (1)
Dr. Yang Ziqi
Elevated prolactin levels, medically known as hyperprolactinemia, can be caused by various factors. Common causes include: 1. **Pituitary adenoma**: Approximately half of hyperprolactinemia cases are associated with pituitary microadenomas or macroadenomas. These benign tumors secrete excessive amounts of prolactin. 2. **Hormonal imbalances**: Physiological changes such as pregnancy, breastfeeding, sleep deprivation, stress, or the use of certain medications may temporarily increase prolactin levels. 3. **Medication effects**: Certain drugs, such as antipsychotics, antihypertensives, or sedatives, can increase prolactin secretion. 4. **Pathological factors**: Hypothyroidism, liver disease, kidney disease, or chronic illnesses may also lead to elevated prolactin levels. 5. **Female reproductive system issues**: Menstrual irregularities, polycystic ovary syndrome (PCOS), or breast stimulation may also cause increased prolactin levels. Note that if abnormal prolactin levels are detected, consultation with a physician is recommended.