How to Interpret the Results of Down Syndrome Screening

Jul 16, 2024 Source: Cainiu Health
Disease description:

I am currently pregnant and have just completed the Down syndrome screening. How do I interpret the results of the Down syndrome screening?

Doctor's answer (1)
Dr. Zhang Lu

Viewing the results of Down syndrome screening mainly includes the following aspects:

  1. Verify personal information to ensure the accuracy of basic details such as gestational age, maternal age, and name.
  2. Pay attention to the blood test results, especially indicators such as free estriol and alpha-fetoprotein. If these indicators fall outside the normal range, it may suggest an increased risk of Down syndrome in the fetus.
  3. Check the risk value by comparing the screening results with the standard values. Generally, a risk value ≥ 1:270 is considered high risk, 1:270–1:1000 is intermediate risk, and <1:1000 is low risk. Pregnant women identified as high-risk may need further diagnostic tests such as amniocentesis or non-invasive prenatal DNA testing.

Down syndrome screening is only an assessment of the fetus's risk for Down syndrome and is not a diagnostic method. Therefore, even if the screening result is high-risk, pregnant women should not panic excessively, but follow medical advice for further examinations.