How is acute aplastic anemia treated?
Disease description:
Sudden fainting; after examination, it was diagnosed as acute aplastic anemia. I would like to know how to treat acute aplastic anemia effectively?
Doctor's answer (1)
Dr. Liu Feng
Acute aplastic anemia is a severe form of bone marrow failure, and its treatment methods include the following:
1. Blood transfusion therapy: Transfusing blood components such as red blood cells and platelets can increase the levels of all three blood cell lines in patients, thereby improving clinical symptoms of infection and bleeding.
2. Drug therapy: Cyclosporine can be used to inhibit the activity of cytotoxic T cells, and androgens can stimulate bone marrow hematopoiesis, improving the patient's ability to produce blood cells and alleviating clinical symptoms.
3. Surgical treatment: Hematopoietic and immune functions can be reconstituted through stem cell transplantation, achieving clinical cure at the stem cell level in patients with acute aplastic anemia.
4. Immunosuppressive therapy: Usually involves the use of cyclosporine A combined with corticosteroids to suppress autoimmune reactions that attack normal hematopoietic cells.
5. Hematopoietic stem cell transplantation: Allogeneic hematopoietic stem cell transplantation is a curative treatment suitable for young patients with an appropriate donor, but it carries high risks, including graft-versus-host disease and graft failure.
