The most common complications of nephrotic syndrome
Disease description:
These days, my father noticed significant swelling and edema. After going to the hospital for examination, he was diagnosed with nephrotic syndrome. I would like to ask about this condition—what is the most common complication of nephrotic syndrome?
Doctor's answer (1)
Dr. Yang Ziqi
The most common complications of nephrotic syndrome mainly include the following:
1. Infection: This is the most frequent complication of nephrotic syndrome. Due to the significant loss of immunoglobulins from the body and the use of corticosteroids and immunosuppressive therapies, patients often experience decreased immunity, making them susceptible to secondary infections, especially respiratory tract infections, with viral infections being common.
2. Thromboembolism: Patients with nephrotic syndrome often lose anticoagulant substances, experience hemoconcentration, and develop hyperlipidemia, which can lead to a hypercoagulable state. This increases the risk of thromboembolic events, particularly renal vein thrombosis and deep vein thrombosis of the lower extremities. Thromboembolism is an important factor affecting the treatment and prognosis of nephrotic syndrome.
3. Acute kidney injury: Some patients with nephrotic syndrome, especially those with severe edema, are prone to developing acute kidney injury when treated with potent diuretics, which may lead to acute renal failure.
