How many years does the rabies vaccine provide protection in humans?

Aug 29, 2024 Source: Cainiu Health
Disease description:

I previously received the rabies vaccine and would like to know how many years it can protect me. I heard the duration is not fixed; how long does the rabies vaccine last in humans?

Doctor's answer (1)
Dr. Yang Ziqi

After completing the full course of rabies vaccination, the antibodies produced in the human body can provide protection for a certain period. However, this duration can be influenced by various factors. The variation in effectiveness is as follows:

1. Generally, after completing the full course of rabies vaccination, the protection can last in the human body for approximately 6 months to 12 months.

2. Antibody decline: If there is another rabies exposure within 6 months after vaccination, re-vaccination is usually not necessary. However, if the exposure occurs more than 6 months after vaccination, a booster dose or a complete re-vaccination regimen may be considered depending on specific circumstances.

3. Management after re-exposure: If another exposure occurs between 6 months and 1 year after completing the vaccination, it is recommended to receive a booster dose. If the exposure occurs more than 1 year after vaccination, a complete re-vaccination schedule is required.

For certain high-risk groups, such as veterinarians, animal control personnel, or individuals living or working in areas with a high incidence of rabies, it is recommended to regularly monitor antibody levels to ensure ongoing protection. If antibody levels fall below the protective threshold, a booster dose may be required.