The function of parathyroid hormone

Parathyroid hormone (PTH) is an important hormone secreted by the parathyroid glands in the human body. It primarily regulates the metabolic balance of calcium and phosphorus. Its mechanism of action is complex and mainly achieved through the following aspects:

1. The main function of parathyroid hormone is to promote the release of calcium ions from bone into the bloodstream, thereby increasing the concentration of calcium ions in the blood. This is important for maintaining stable blood calcium levels and ensuring the normal functioning of tissues such as nerves and muscles.

2. PTH also enhances the reabsorption of calcium ions in the kidneys while reducing phosphorus reabsorption. Additionally, it promotes the synthesis of active vitamin D, which enhances the intestinal absorption of calcium, thereby indirectly increasing blood calcium levels. This further helps regulate the levels of both blood calcium and phosphorus. This fine regulation ensures the balance of calcium and phosphorus metabolism in the body and prevents various diseases caused by abnormalities in calcium and phosphorus metabolism.

In maintaining the balance of calcium and phosphorus within the body, parathyroid hormone plays a significant role in bone health, neuromuscular function, and the cardiovascular system, among other areas.