Is fasting required for Down syndrome screening?

Generally, fasting is not required for Down syndrome screening. Down syndrome screening is an important prenatal test during pregnancy, designed to assess the risk of fetal chromosomal abnormalities, such as Down syndrome. By measuring specific biomarkers in the mother's serum and combining this data with factors such as maternal age and gestational age, the risk of fetal abnormalities can be calculated comprehensively. The dietary status of the pregnant woman generally does not significantly affect the test results. Therefore, pregnant women can undergo screening after eating appropriately and do not need to remain fasting specifically.

However, pregnant women should still avoid consuming high-sugar, high-fat, and spicy or irritating foods before screening to maintain optimal physical condition and reduce the occurrence of lipemia, thereby avoiding unnecessary interference with the test results. Down syndrome screening is usually performed between 15 and 20 weeks of pregnancy, and pregnant women should schedule an appointment with the hospital in advance to avoid missing the optimal screening window. On the day before screening, pregnant women should maintain a light diet and avoid consuming foods that may affect the test results. To ensure the accuracy of the screening results, it is recommended to consult a doctor before the test to understand the specific screening methods and precautions.