Does Dong'e Ejiao contain estrogen?

Feb 27, 2025 Source: Cainiu Health
Disease description:

In daily life, we often hear that Dong'e Ejiao can improve one's complexion and beautify the skin. I would like to ask the doctor: does Dong'e Ejiao contain estrogen?

Doctor's answer (1)
Dr. Bai Hongmei

Donkey-hide gelatin (Ejiao) does not contain estrogen.

Donkey-hide gelatin is a traditional Chinese medicinal ingredient made from donkey skin processed through a special technique. Its primary components include collagen, amino acids, calcium, iron, other trace elements, and small amounts of polypeptides. It is known to have multiple health benefits such as invigorating qi and nourishing blood, enhancing immune function, strengthening muscles and bones, and beautifying the skin. However, current scientific studies have not found estrogen or components with significant estrogenic activity in donkey-hide gelatin. Its beneficial effects are largely attributed to its rich collagen and amino acid content, which can positively improve skin elasticity, promote blood circulation, and enhance immunity. This makes donkey-hide gelatin a high-quality health food, especially beneficial for women in regulating qi and blood, improving anemia, and enhancing skin quality.

However, even if some traditional herbs may contain微量 phytoestrogen-like substances, the bioavailability and actual effects of donkey-hide gelatin in the human body are significantly lower than those of directly ingested animal-derived or synthetic estrogens.