What causes general weakness and leg fatigue?

Mar 22, 2025 Source: Cainiu Health
Disease description:

A friend of mine has recently been feeling weak all over with weak and shaky legs. We are not sure what is causing this. Doctor, may I ask what are the possible reasons for feeling weak all over with weak and shaky legs?

Doctor's answer (1)
Dr. Lv Zhiqin

General weakness and leg fatigue can be caused by overexertion, lack of sleep, malnutrition, hypoglycemia, anemia, and other factors.

1. Overexertion: Prolonged heavy physical labor or high-intensity exercise can lead to excessive physical exhaustion and muscle strain, resulting in general weakness and leg fatigue.

2. Sleep deprivation: Chronic late nights or poor sleep quality can cause insufficient rest, inadequate recovery of the body, and a fatigued nervous system, leading to feelings of general weakness and leg fatigue.

3. Malnutrition: An unbalanced diet lacking essential nutrients can result in decreased bodily functions and cause symptoms of general weakness and leg fatigue.

4. Hypoglycemia: When blood sugar levels are too low, the body cannot supply sufficient energy for the muscles and nervous system, causing general weakness and leg fatigue.

5. Anemia: Anemia leads to a reduced number of red blood cells, causing oxygen deficiency in the body and muscles, thereby resulting in symptoms of general weakness and leg fatigue.

Maintain adequate sleep duration and improve sleep quality in daily life. Eat a balanced diet and ensure sufficient nutrient intake.