Is it a problem if thrombin levels are elevated?
Disease description:
Elevated thrombin levels were found during a physical examination. Recently, there has been occasional gum bleeding and unexplained bruising on the body. Is elevated thrombin really a concern? Does it have a significant impact on the body?
Doctor's answer (1)
Dr. Liu Feng
In general, elevated thrombin levels may indicate certain health issues.
Prothrombin time (PT) and the international normalized ratio (INR) are commonly used clinical indicators for evaluating coagulation function. When prothrombin time shortens or the INR decreases, it suggests increased thrombin activity, which may imply a pathological condition that can easily lead to various bleeding symptoms, such as gum bleeding, nosebleeds, and hematuria. In severe cases, it may even result in cerebral hemorrhage.
Elevated thrombin levels may be caused by a hypercoagulable state, which is commonly seen in conditions such as deep vein thrombosis and pulmonary embolism. Additionally, certain autoimmune diseases, infectious diseases, and the use of oral contraceptives or hormone replacement therapy can also lead to increased thrombin levels. Patients with elevated thrombin should undergo a comprehensive evaluation, including detailed medical history collection, physical examination, and necessary laboratory tests, to determine the underlying cause.
Patients should also maintain healthy lifestyle and dietary habits in daily life to avoid exacerbating the condition or triggering other complications.
