Mechanism of Blood Glucose Reduction by Vildagliptin Tablets

Hello, this drug exerts its effects through two primary mechanisms: 1. It promotes insulin secretion by directly acting on receptors located on pancreatic beta cells, thereby lowering blood glucose levels. 2. It reduces glucagon secretion; since glucagon elevates blood glucose, decreased glucagon secretion indirectly contributes to lower blood glucose levels. Additionally, the drug inhibits dipeptidyl peptidase-4 (DPP-4) activity in the body, leading to increased endogenous levels of glucagon-like peptide-1 (GLP-1), which further helps lower blood glucose.