Normal range of human plasma pH
Feb 27, 2023
Source: Cainiu Health
Dr. Zhang Heyang
Introduction
The normal pH range of human plasma is typically between 7.35 and 7.45. Plasma pH generally serves as an indicator of hydrogen ion concentration or the acidity and alkalinity of body fluids. In addition, patients should promptly go to the hospital for examination. If the condition is caused by nephrotic syndrome, medications such as hydrochlorothiazide tablets, chlorambucil, and cyclosporine tablets may be prescribed under a doctor's guidance.
The normal pH range of human plasma typically falls between 7.35 and 7.45.
Plasma pH generally reflects the hydrogen ion concentration or acidity/alkalinity of body fluids. It is defined as the negative logarithmic value of hydrogen ion concentration in arterial plasma before separation of blood cells, with a normal range of 7.35–7.45. In healthy individuals, blood pH remains relatively stable due to buffering systems composed of acid- and base-resisting substances in the blood, along with normal respiratory and excretory functions. However, if these regulatory mechanisms are impaired or affected by diseases such as nephrotic syndrome, acid-base imbalances may occur.
If plasma pH falls below the normal range, it may indicate acidosis—such as respiratory acidosis or metabolic acidosis. Conversely, a pH above the normal range suggests alkalosis, including respiratory alkalosis or metabolic alkalosis, which can have serious effects on the patient's health.
In addition, patients should promptly seek medical evaluation. If the condition is caused by nephrotic syndrome, medications such as hydrochlorothiazide tablets, chlorambucil, or cyclosporine tablets may be prescribed under a doctor’s guidance for treatment.
