Diagnostic criteria for severe hepatic insufficiency

Apr 12, 2023 Source: Cainiu Health
Dr. Jiang Weimin
Introduction
Severe hepatic insufficiency refers to a state in which liver function is seriously impaired, failing to maintain normal physiological functions. Diagnostic criteria include abnormal liver function tests, hepatic encephalopathy, and ascites. Additionally, impaired liver function may lead to renal dysfunction, manifested as reduced urine output and elevated serum creatinine levels. If severe hepatic insufficiency is suspected, prompt medical attention is necessary.

Severe liver dysfunction refers to a state in which liver function is seriously impaired and unable to maintain normal physiological functions. Its diagnostic criteria include abnormal liver function tests, hepatic encephalopathy, ascites, etc., as detailed below:

1. Abnormal liver function tests

Elevated serum bilirubin levels, decreased serum albumin levels, prolonged plasma prothrombin time, etc.

2. Hepatic encephalopathy

Due to the liver's inability to clear toxins from the body, neurological dysfunction occurs, manifesting as disturbances in consciousness, altered mental status, tremors of the hands and feet, etc.

3. Ascites

Impaired liver function leads to decreased plasma protein levels, causing fluid to leak from blood vessels into the abdominal cavity, resulting in ascites.

In addition, liver dysfunction may also lead to kidney impairment, manifested as reduced urine output, elevated blood creatinine levels, etc. In summary, the diagnosis of severe liver dysfunction involves multiple aspects and requires comprehensive evaluation of the patient's clinical manifestations, liver function tests, imaging studies, and other factors. If you suspect that you or someone else has severe liver dysfunction, prompt medical attention for diagnosis and treatment is essential.


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