Does povidone-iodine expire?

Jan 23, 2025 Source: Cainiu Health

Dr. Yang Ziqi

Introduction

Under normal circumstances, povidone-iodine can expire. If povidone-iodine is needed, it should be used according to medical advice. The main components of povidone-iodine are polyvinylpyrrolidone and elemental iodine, which may gradually change during storage. Due to its strong oxidizing properties, povidone-iodine easily reacts with oxygen in the air, leading to a gradual decrease in its active ingredients and thereby affecting its disinfecting effectiveness.

Generally speaking, povidone-iodine can expire. If povidone-iodine needs to be used, it should be done under medical guidance. Detailed analysis is as follows:

The main components of povidone-iodine are polyvinylpyrrolidone and elemental iodine, which can gradually change during storage. Due to its strong oxidizing properties, povidone-iodine easily reacts with oxygen in the air, causing a gradual reduction in its active ingredients and thereby affecting its disinfecting effectiveness. Additionally, the iodine in povidone-iodine can gradually volatilize, leading to a decrease in the content of active iodine and further reducing its disinfecting capability.

Moreover, the shelf life of povidone-iodine is also influenced by packaging methods and storage conditions. If the packaging of povidone-iodine is not sufficiently sealed, or if the storage environment is not cool and dry enough, it can accelerate the loss and volatilization of its active ingredients. Especially in high temperature and humid environments, the shelf life of povidone-iodine will be significantly shortened.

In daily life, povidone-iodine should be stored in a cool, dry, and well-ventilated place, avoiding direct sunlight.

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