What Are the Different Types of Sleeping Pills?

Jul 19, 2021 Source: Cainiu Health
Dr. Yang Jun
Introduction
1. Short-acting agents: Suitable for individuals with difficulty falling asleep or those experiencing occasional or transient insomnia. Example: Dormicum® (chemical name: midazolam). 2. Intermediate-acting agents: Suitable for individuals with light sleep and frequent dreaming. Examples: Estazolam (brand name: Sulex®) and alprazolam (brand name: Xanax®). 3. Long-acting agents: Suitable for individuals with light sleep and early morning awakening. Example: Valium® (chemical name: diazepam).

Due to the wide variety of hypnotic drugs available, different types are indicated for distinct sleep disorders. However, it is important to note that although hypnotics are highly effective in treating insomnia, they also carry significant adverse effects for patients—thus, their use should be minimized whenever possible. So, what are the main categories of hypnotic drugs? The following section addresses this question.

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What Are the Main Types of Hypnotic Drugs?

1. Short-acting hypnotics

These are suitable for individuals with difficulty falling asleep or those experiencing occasional or transient insomnia. “Su Mian An” (generic name: midazolam), also known as “midazolam,” has a short duration of action. It is contraindicated in pregnant women and patients with myasthenia gravis; it is not recommended for patients with schizophrenia or severe depression. “Si Nuo Si” (generic name: zolpidem) acts rapidly and is indicated for short-term treatment. However, common side effects include diarrhea, headache, and memory impairment. It is contraindicated in pregnant women, lactating women, and children under 15 years of age; elderly patients and those with hepatic or renal insufficiency should use it with caution.

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2. Intermediate-acting hypnotics

These are appropriate for individuals with light, fragmented sleep accompanied by frequent dreaming. “Shu Le An Ding” (generic name: estazolam) has relatively few adverse effects; however, elderly, frail, or pediatric patients must follow medical advice when using it. “Jia Jing An Ding” (generic name: alprazolam) possesses anxiolytic properties. Its adverse effects may include dizziness, constipation, ataxia (with high doses), rash, and leukopenia. Due to its potential for dependence, it should be used cautiously in patients with depressive disorders; dosage should be halved in elderly or frail individuals.

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3. Long-acting hypnotics

These are indicated for individuals with light sleep and early-morning awakening. “An Ding” (generic name: diazepam) has a broad therapeutic spectrum, including efficacy against anxiety and phobic disorders, as well as tension-type headaches. Its adverse effect profile is similar to that of “Jia Jing An Ding.” It is contraindicated in patients with glaucoma or myasthenia gravis, and should be used with caution in elderly patients, pregnant women, and lactating women. “Fu An Ding” (generic name: flurazepam) is completely absorbed after oral administration and acts rapidly—particularly beneficial for patients with difficulty initiating sleep. Gastrointestinal disturbances and dependency may occur. Caution is advised in patients with hepatic or renal insufficiency and in pregnant women.

The above outlines the major classifications of hypnotic drugs. We hope this information proves helpful to you.

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