What does it mean if endometrial biopsy CD138 is positive?

Sep 13, 2022 Source: Cainiu Health
Disease description:

My sister said her endometrial biopsy at the hospital showed a positive CD138 result. I'm a bit concerned and would like to know what a positive CD138 in an endometrial biopsy means.

Doctor's answer (1)
Dr. Lv Aiming
A positive CD138 result in endometrial biopsy indicates a likely association with endometritis. CD138 is a specific marker for plasma cells, and a positive test suggests a higher probability of inflammation in the endometrium. Endometritis is an inflammatory response caused by infection of the endometrium with pathogens, which may lead to symptoms such as lower abdominal pain, abnormal vaginal discharge, menstrual irregularities, and fever.