What are the side effects of grape seed?

Generally, consuming excessive amounts of grape seeds may lead to reduced appetite, dizziness, allergic reactions, indigestion, and gastrointestinal damage. The details are as follows:

1. Reduced Appetite

Grape seeds contain tannins, which can coagulate proteins on mucosal surfaces, affect glandular secretions, and disrupt normal gastrointestinal function. This slows down the digestive and absorptive processes in the gastrointestinal tract, leading to loss of appetite.

2. Dizziness

Grape seeds can lower blood pressure and reduce blood lipids, helping prevent thrombosis. However, when blood pressure drops too much, it may cause dizziness.

3. Allergic Reactions

Some individuals may be allergic to grape seeds. After consumption, they might develop symptoms such as skin redness, swelling, and itching. If an allergic reaction occurs, prompt medical attention is necessary. Under a doctor's guidance, medications such as chlorpheniramine maleate tablets or loratadine tablets can be used for treatment.

4. Indigestion

Grape seeds are rich in amino acids, proanthocyanidins, and minerals. When consumed in moderation, they offer antioxidant benefits and support cardiovascular health. However, grape seeds also contain tannins and other potentially harmful substances. Tannins produce a strong astringent taste, and excessive intake may irritate the gastrointestinal tract, causing indigestion.

5. Gastrointestinal Injury

If grape seeds enter the digestive tract, their sharp ends may potentially cause physical damage to the gastrointestinal lining. A safer way to consume grape seeds is to blend whole grapes (including skin and seeds) in a high-speed blender, allowing you to ingest both the skin and seeds without irritating or injuring the gastrointestinal tract.

It is recommended to use grape seed-based supplements only under medical supervision and avoid excessive consumption of grape seeds.