What is the success rate of first-generation IVF?
Feb 07, 2023
Source: Cainiu Health
Dr. Lv Aiming
Introduction
For first-generation IVF, if the patient has a normal uterine cavity shape, normal endometrium, no other underlying diseases, and is approximately under 35 years of age, the success rate for this group of patients can reach 50%–60%. However, if the embryo's developmental potential is poorer—such as in older patients—the success rate of IVF, whether first or second generation, will decrease.
If the uterine cavity morphology is normal, the endometrium is healthy, there are no other underlying medical conditions, and the patient's age is under approximately 35, the success rate of first-generation IVF can reach 50%–60%.
First-generation IVF, also known as artificial insemination, is an assisted reproductive technology that helps individuals who are unable to ovulate or conceive naturally. In this procedure, doctors fertilize eggs with sperm in a laboratory setting and then transfer the resulting embryos into the recipient's uterus. This method is typically used for individuals who cannot ovulate, suffer from infertility, or those who have fertility but choose not to conceive immediately. However, if the male partner has poor sperm quality—such as low sperm count or weak sperm motility—first-generation IVF may not be effective, as these conditions cannot be resolved with medication alone. This limitation led to the development of second-generation IVF technology.
As women age, egg quality declines. Therefore, even when embryos are successfully transferred, their developmental potential may be lower compared to embryos from younger patients. Consequently, the success rates of both first- and second-generation IVF decrease with advancing age.
