What should be done if carbohydrate antigen 125 (CA125) levels are elevated?
Feb 23, 2023
Source: Cainiu Health
Dr. Peng Xiaodong
Introduction
Elevated levels of carbohydrate antigen CA125 can generally be managed through dynamic monitoring, daily lifestyle adjustments, and medication. For mild elevations in carbohydrate antigen 125, dynamic observation is recommended. If the increase is slight—normal values being 0 to 10, and mildly elevated levels ranging from 12 to 20—dynamic observation alone is usually sufficient.
Elevated levels of carbohydrate antigen CA125 can generally be managed through dynamic monitoring, daily lifestyle adjustments, medication, and other approaches.
1. Dynamic Monitoring
For mildly elevated carbohydrate antigen CA125 levels, dynamic monitoring may be an appropriate management strategy. The normal reference range is typically 0–10 U/mL. If the level rises slightly to between 12 and 20 U/mL, regular follow-up observation is usually sufficient.
2. Daily Lifestyle Adjustments
In women, during the first three months of pregnancy—known as early pregnancy—CA125 levels may temporarily increase when tested. This is considered a normal physiological phenomenon, and the levels typically return to normal after the early pregnancy period. Pregnant women should ensure adequate rest and consume a light, balanced diet.
3. Medication
Endometriosis is a condition caused by the abnormal growth of endometrial tissue outside its normal location, which may lead to elevated CA125 levels. Patients may also experience symptoms such as dysmenorrhea (painful menstruation) and menstrual irregularities. Under medical supervision, medications such as gestrinone capsules, norethisterone tablets, or dydrogesterone tablets may be prescribed.
In addition, if elevated CA125 levels are due to ovarian cancer, prompt medical evaluation and treatment at a hospital are recommended. Chemotherapy may be necessary depending on the clinical situation.
