Measures for managing hemolytic reactions caused by blood transfusion

Feb 26, 2023 Source: Cainiu Health
Dr. Zhang Heyang
Introduction
Management of hemolytic transfusion reactions generally includes immediate cessation of the transfusion, maintenance of intravenous access, and measures to protect kidney function. In addition, after a hemolytic transfusion reaction occurs, close monitoring of vital signs and urine output is essential, with prompt treatment initiated if any abnormalities are detected. If oliguria or anuria develops, acute renal failure should be suspected and shock management should be initiated immediately.

Management of hemolytic reactions caused by blood transfusion generally includes immediate cessation of transfusion, maintenance of intravenous access, and protection of kidney function.

1. Immediately stop the transfusion

If a clear hemolytic reaction occurs during blood transfusion, the transfusion must be stopped immediately, and the physician should be informed for emergency management. During this time, any remaining blood should be preserved, and blood samples from the patient should be collected for blood typing and cross-matching tests.

2. Maintain intravenous access

When a hemolytic reaction occurs during transfusion, in addition to stopping the transfusion immediately, intravenous access should be maintained to allow for emergency intravenous fluid administration if needed.

3. Protect kidney function

Hemolytic reactions during transfusion may cause kidney damage, so it is important to protect renal function. Bilateral lumbar blockade or application of warm compresses (e.g., hot water bag) may help relieve renal vascular spasm.

In addition, after a hemolytic transfusion reaction, close monitoring of vital signs and urine output is essential. Any abnormalities should be treated promptly. If oliguria or anuria occurs, acute renal failure should be suspected, and anti-shock treatment should be initiated immediately.

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