Is low-grade squamous intraepithelial lesion serious?

Feb 27, 2023 Source: Cainiu Health
Dr. Qi Zhirong
Introduction
Low-grade squamous intraepithelial lesion (LSIL) is not severe. LSIL may be associated with inflammation, high-risk HPV infection, or low-grade cervical lesions. In addition, factors such as infection, prolonged disease course, and inadequate care may also contribute to this condition. Patients should visit a local hospital for examination and receive targeted treatment under the guidance of a physician.

In general, low-grade squamous intraepithelial lesions (LSIL) are not serious. LSIL may be associated with inflammation, high-risk HPV infection, or low-grade cervical lesions. Specific causes are analyzed as follows:

1. Inflammation

Low-grade squamous intraepithelial lesions are usually caused by local inflammatory changes. Chronic and recurrent inflammation can lead to mild cellular abnormalities in the squamous epithelium. Patients may use anti-inflammatory medications under a doctor's guidance, such as Fuyankang lotion or metronidazole tablets, to help alleviate symptoms.

2. High-risk HPV virus

HPV is typically transmitted through sexual activity. Women with relatively weak vaginal immune defenses are more susceptible to HPV infection. Prolonged infection with high-risk HPV types can result in low-grade squamous intraepithelial lesions. Under medical supervision, patients may be treated with medications such as anti-HPV bio-protein dressings or fluorouracil ointment.

3. Low-grade cervical lesions

Low-grade lesions may occur due to multiple sexual partners, cross-infection, or presence of sexually transmitted infections, all of which may contribute to LSIL. Under a doctor’s guidance, treatments such as local cryotherapy or laser therapy may be used.

In addition, other factors such as infection, prolonged disease duration, or inadequate care may also lead to these conditions. Patients should visit a local hospital for evaluation and receive targeted treatment under medical supervision.

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