Why did fibrosis still occur despite continuous antiviral treatment?
Apr 04, 2023
Source: Cainiu Health
Dr. Guo Xiheng
Introduction
Persistent antiviral therapy but still developing fibrosis may be related to inflammation, disease progression, or conditions such as non-alcoholic fatty liver disease. Professional treatment can be administered under a doctor's guidance based on symptoms. However, if liver inflammation is caused by bacterial infection, it may lead to localized fibrosis. In addition, ongoing viral activity with fibrosis may also be associated with low-level residual HBV.
Persistent antiviral therapy with ongoing fibrosis may be related to inflammation, disease progression, or conditions such as non-alcoholic fatty liver disease. Professional treatment should be administered under a doctor's guidance based on specific symptoms.
1. Inflammation
Although antiviral treatment is ongoing, if bacterial infection causes hepatic inflammation, localized fibrosis may develop. In severe cases, medications such as adefovir dipivoxil tablets or metronidazole tablets may be prescribed under medical supervision.
2. Disease Progression
Fibrosis is part of the progression from chronic liver disease to cirrhosis. If proper care is not maintained during treatment and the condition worsens, fibrosis may become more severe. Medications such as oseltamivir phosphate capsules or ribavirin tablets may be used as directed by a physician.
3. Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-alcoholic fatty liver disease can disrupt normal liver metabolism, leading to liver fibrosis. Treatment may include hepatoprotective agents such as hepaprotectant tablets or bifendate tablets, as recommended by a doctor.
In addition, persistent fibrosis despite antiviral therapy may also be associated with low-level residual HBV infection.
