How much viral load in a "small three positive" case requires antiviral treatment?

Jun 05, 2023 Source: Cainiu Health
Dr. Jiang Weimin
Introduction
The decision on when to start antiviral treatment for "minor three positives" should be based on individualized assessment and diagnosis. "Minor three positives" refers to a hepatitis B virus infection status characterized by negative hepatitis B surface antigen, negative hepatitis B surface antibody, and positive hepatitis B core antibody. The management and treatment of hepatitis B virus infection should be determined according to specific circumstances, including the type of infection, stage of infection, liver function, and other comprehensive factors.

  The decision on when to initiate antiviral treatment for "minor three positives" depends on individual circumstances and requires personalized diagnosis and management. The specific analysis is as follows:

  "Minor three positives" refers to a hepatitis B virus (HBV) infection status characterized by negative hepatitis B surface antigen (HBsAg), negative hepatitis B surface antibody (anti-HBs), and positive hepatitis B core antibody (anti-HBc). The treatment and management of HBV infection should be determined based on individual factors, including the type and stage of infection, liver function, and other comprehensive considerations. Therefore, the decision on when to initiate antiviral therapy for "minor three positives" must be made through individualized assessment and clinical evaluation. The primary goals of managing HBV infection are to prevent or reduce liver damage caused by the virus and to lower the risk of serious complications such as cirrhosis and liver cancer. Under medical supervision, medications such as entecavir dispersible tablets or tenofovir alafenamide fumarate tablets may be used for treatment.

  During treatment, it is recommended to regularly monitor liver function and viral load, avoid alcohol consumption, and refrain from using hepatotoxic drugs to protect liver health. If any other discomfort or symptoms arise, prompt medical consultation at a hospital is advised.


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