The difference between roxithromycin and clarithromycin

Apr 12, 2023 Source: Cainiu Health
Dr. Jiang Weimin
Introduction
The differences between roxithromycin and clarithromycin lie in their distinct physicochemical properties, the types of bacteria they target, and the diseases they treat. Roxithromycin has a density of 1.25 g/cm³ and is relatively soluble in methanol or ether. Clarithromycin has a density of 1.18 g/cm³ and is slightly soluble in ethanol and methanol.

The differences between roxithromycin and clarithromycin lie in their distinct physicochemical properties, targeted bacteria, and the diseases they treat.

1. Different physicochemical properties

Roxithromycin has a density of 1.25 g/cm³ and is relatively soluble in methanol or ether. Clarithromycin has a density of 1.18 g/cm³ and is slightly soluble in ethanol and methanol.

2. Different target bacteria

Roxithromycin primarily targets anaerobic bacteria, mycoplasma, and Gram-positive bacteria. Clarithromycin, on the other hand, targets bacteria such as streptococcus, Staphylococcus aureus, and Haemophilus influenzae.

3. Different indications

Roxithromycin is mainly used to treat conditions such as Mycoplasma pneumoniae-induced pneumonia and non-gonococcal urethritis caused by Chlamydia trachomatis. Clarithromycin is primarily used for treating soft tissue infections, sinusitis, folliculitis, and similar conditions.

Patients are advised to use these medications only under the guidance of a qualified physician and should avoid self-medication. If any adverse reactions occur during treatment, medication should be stopped immediately and medical attention sought promptly.


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