How to test for insulin resistance
Apr 26, 2023
Source: Cainiu Health
Dr. Pan Yongyuan
Introduction
Insulin resistance is assessed using tests such as fasting insulin, C-peptide levels, and the euglycemic insulin clamp technique. Fasting insulin level measurement reflects pancreatic β-cell secretory function and helps evaluate the state of insulin resistance. C-peptide level testing indicates the presence of insulin resistance. The euglycemic insulin clamp technique avoids the impact of endogenous insulin deficiency and hypoglycemia on insulin sensitivity during testing.
Insulin resistance can be assessed through tests such as fasting insulin, C-peptide levels, and the euglycemic insulin clamp technique. Specific details are as follows:
1. Fasting Insulin
Fasting insulin levels are measured after the patient has fasted overnight for 12 hours. This test reflects pancreatic β-cell secretory function and indicates the presence of insulin resistance.
2. C-Peptide Levels
C-peptide level testing can reflect the status of insulin resistance. For example, when insulin levels in the body are elevated but C-peptide levels remain normal, this suggests the presence of insulin resistance.
3. Euglycemic Insulin Clamp Technique
This is an effective method for assessing insulin resistance, as it avoids the influence of endogenous insulin deficiency and hypoglycemia on insulin sensitivity during testing.
In addition, the homeostasis model assessment of insulin resistance (HOMA-IR) index can also be used to evaluate insulin resistance. If abnormalities are detected, prompt medical consultation and treatment under a physician's guidance are necessary.
