Which is better: Xiaoke Pill or Metformin?

Dec 12, 2025 Source: Cainiu Health
Dr. Sun Lianqing
Introduction
Xiaoke Pill and metformin have no absolute superiority over each other; their glucose-lowering mechanisms and target populations differ, so the choice should be based on individual medical conditions. Xiaoke Pill contains glibenclamide and herbal components, offering strong hypoglycemic effects; metformin is a first-line antidiabetic drug with high safety and the ability to improve insulin resistance. Always consult a doctor before taking medication and avoid adjusting treatment regimens on your own.

There is no absolute superiority between Xiaoke Pill and metformin, as they differ in glucose-lowering mechanisms and target populations; the choice should be based on individual medical conditions. Xiaoke Pill contains glibenclamide and herbal components, offering strong blood sugar-lowering effects. Metformin, a first-line antidiabetic medication, has high safety and helps improve insulin resistance. Always consult a doctor before starting treatment and avoid adjusting your regimen without medical advice.

Xiaoke Pill is suitable for patients with mild to moderate type 2 diabetes, especially those experiencing significant blood glucose fluctuations. Its Western medicine component rapidly lowers blood sugar, while the herbal ingredients assist in metabolic regulation. However, it may cause hypoglycemia, and caution is advised for individuals with impaired liver or kidney function. Metformin is recommended for type 2 diabetic patients whose blood sugar remains uncontrolled by diet alone. It can be used alone or in combination with other drugs, reducing intestinal glucose absorption with minimal impact on body weight. Common side effects are gastrointestinal discomfort, which often diminish over time with continued use.

In daily life, regularly monitor blood glucose levels, control staple food intake, consume more vegetables and high-quality protein, avoid high-sugar and high-fat foods, engage in moderate exercises such as walking or tai chi, maintain regular sleep patterns, and avoid staying up late to help achieve stable blood glucose control.

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