Is Sophora flavescens gel effective for HPV infection?
Matrine gel is generally ineffective against HPV infection and is not recommended for use. The detailed analysis is as follows:
Matrine gel is composed of total alkaloids extracted from Sophora flavescens and has antibacterial and anti-inflammatory effects in clinical use. It is primarily used to treat chronic gynecological inflammations such as leukorrhea, trichomonal vaginitis, and vulvovaginal candidiasis. HPV infection is usually caused by a decline in human immunity leading to infection with the human papillomavirus. Since matrine gel does not inhibit replication of the human papillomavirus nor enhance immune function, it is not recommended.
For HPV infection, antiviral medications prescribed by a doctor can be used. Commonly used drugs include imiquimod cream, fluorouracil ointment, and tacrolimus ointment.