Can I get a nucleic acid test after receiving the HPV 9-valent vaccine?
Dec 04, 2025
Source: Cainiu Health
Dr. Zhang Lu
Introduction
The function of the nine-valent vaccine is to stimulate the body to produce antibodies against human papillomavirus, thereby preventing related infections. Its components do not cross-react with the target pathogens of nucleic acid testing. Nucleic acid testing detects pathogens by amplifying specific nucleic acid sequences; the vaccine does not interfere with this testing process, nor does it cause false-positive or false-negative results.
It is safe to undergo nucleic acid testing after receiving the HPV九-valent vaccine, as there is no conflict between the two. They do not interfere with each other in terms of test results or the vaccine's immune effectiveness. If you experience persistent fever, severe allergic reactions, or other abnormalities after vaccination, it is recommended to seek medical attention promptly.
The purpose of the nine-valent vaccine is to stimulate the body to produce antibodies against human papillomavirus (HPV), thereby preventing related infections. Its components do not overlap with the target pathogens of nucleic acid testing. Nucleic acid testing detects specific pathogens by amplifying their genetic sequences, and the vaccine does not interfere with this process, nor does it cause false-positive or false-negative test results.
After receiving the nine-valent vaccine, some individuals may experience transient adverse reactions such as redness and swelling at the injection site or mild fever. These reactions are unrelated to the sampling and testing procedures of nucleic acid testing and will not be exacerbated by undergoing a test. The throat or nasal swabbing involved in sample collection also does not affect the vaccine-induced immune response in the body.
After vaccination, keep the injection site clean and dry to avoid infection from water exposure. Rinse your mouth with water before sample collection to prevent food residue in the mouth from affecting sampling accuracy. Maintain personal protection, wear a mask promptly after testing, and maintain regular sleep patterns to avoid excessive fatigue, helping your body smoothly transition through the adaptation period following vaccination.
