What is the difference between cardiac enzymes and the three markers for myocardial infarction?
The differences between cardiac enzyme tests and the three-marker panel for myocardial infarction lie in the tested indicators, the strength of specificity, and testing speed. Specific details are as follows:
1. Different tested indicators
Cardiac enzyme tests mainly include five markers: creatine kinase (CK), creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH), LDH isoenzymes, and aspartate aminotransferase (AST). The three-marker panel for myocardial infarction includes myoglobin, troponin, and creatine kinase.
2. Differences in specificity
CK-MB has relatively high myocardial specificity. However, elevations in the other four markers do not necessarily indicate myocardial cell injury or necrosis, so the overall specificity of cardiac enzyme tests is relatively low. In contrast, troponin and CK-MB have higher specificity for myocardial tissue. Particularly, elevated troponin levels typically result exclusively from myocardial cell damage or necrosis, giving it even greater specificity.
3. Differences in testing speed
Cardiac enzyme tests are usually performed using large biochemical analyzers, which take longer to produce results. In contrast, the three-marker panel for myocardial infarction can often be completed rapidly at the bedside, providing quicker results.
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