What causes adenomyosis in a 53-year-old postmenopausal woman?
May 14, 2023
Source: Cainiu Health
Dr. Lv Aiming
Introduction
A 53-year-old woman was diagnosed with adenomyosis after menopause. The exact cause of adenomyosis has not been fully clarified, but it is generally associated with abnormal hormone secretion, uterine procedures, endometritis, reproductive tract obstruction, hyperandrogenism, and hyperprolactinemia, all of which may contribute to the development of adenomyosis. It is recommended that patients visit a gynecology department at a hospital for proper diagnosis and follow medical advice regarding appropriate medication. Surgical treatment may be necessary in some cases.
A 53-year-old postmenopausal woman diagnosed with adenomyosis may have developed the condition due to hormonal imbalances, uterine procedures, endometritis, or other factors. Follow-up observation is recommended, and treatment should be administered under medical guidance if necessary. Detailed analysis is as follows:
1. Hormonal Imbalance
Adenomyosis commonly occurs in women aged 35–50, which coincides with the perimenopausal period. During this phase, ovarian function begins to decline and atrophy, ovulation decreases or ceases, estrogen levels become relatively elevated, progesterone levels drop, and ovarian dysfunction leads to excessive endometrial proliferation, triggering adenomyosis. Regular follow-up is advised. If symptoms are severe, surgical intervention may be considered when necessary, such as endometrial resection, excision of adenomyosis lesions, or total hysterectomy.
2. Uterine Procedures
Previous uterine surgeries or improper intraoperative techniques may implant endometrial fragments into the myometrium, causing myometrial injury and leading to the disease. It is recommended that patients take medications such as enteric-coated aspirin tablets, mifepristone tablets, or injectable ozagrel sodium under a doctor's supervision.
3. Endometritis
Endometrial inflammation can damage the basal layer of the endometrium, allowing endometrial glands and stroma to invade the uterine muscle layer, resulting in dysmenorrhea, menstrual irregularities, and uterine enlargement. Patients may take prescribed oral medications such as doxycycline hydrochloride tablets, metronidazole tablets, or clindamycin hydrochloride capsules.
In addition, conditions such as reproductive tract obstruction, hyperandrogenism, and hyperprolactinemia may also contribute to adenomyosis. Patients are advised to visit a gynecologist at a hospital for proper diagnosis. Doctors will develop an individualized treatment plan based on the patient’s specific condition. When necessary, surgical treatments such as total hysterectomy may be performed.
