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Is the hemorrhagic fever vaccine effective for lifelong immunity?

Dec 02, 2025 Source: Cainiu Health
Dr. Li Feng
Introduction
The hemorrhagic fever vaccine does not provide lifelong immunity. After vaccination, individuals gain immune protection for a certain period, the duration of which varies among individuals. Follow-up precautions should be taken according to vaccination history and personal health status. For high-risk populations frequently exposed to rodents or their excretions, it is recommended to undergo regular antibody testing after completing the primary immunization series, and receive booster doses promptly based on test results to maintain effective antibody levels.

Hemorrhagic fever vaccines do not provide lifelong immunity. After vaccination, individuals gain immune protection for a certain period, but the duration varies among individuals. Follow-up precautions should be taken based on vaccination history and personal health conditions.

Hemorrhagic fever vaccines work by stimulating the body's immune system to produce specific antibodies that protect against the relevant viral infections. Clinical data show that after completing the full vaccination schedule as recommended, immune protection typically lasts 5 to 10 years. Over time, antibody levels in the body gradually decline, leading to a progressive reduction in protective efficacy. The effectiveness of immunity is influenced by multiple factors. Individuals who complete the entire vaccination series according to the recommended schedule tend to develop more robust antibody responses and have more stable protection periods. However, individual differences in immune function and exposure risks after vaccination can also affect how long the protection lasts.

For high-risk populations frequently exposed to rodents or their excreta, it is recommended to undergo regular antibody testing after completing primary immunization. Booster doses should be administered promptly based on test results to maintain effective antibody levels.

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Can you receive the hemorrhagic fever vaccine if you have a cold?
Under normal circumstances, the hemorrhagic fever vaccine should not be administered during a cold. When suffering from a cold, the body's immune resistance is relatively weak, making it more susceptible to hemorrhagic fever virus infection; however, vaccination against hemorrhagic fever is not recommended during this period. The hemorrhagic fever vaccine itself can easily cause fever, and if administered while having a cold, the likelihood of developing fever would significantly increase.
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Can you drink alcohol after receiving the hemorrhagic fever vaccine?
In general, alcohol consumption is not recommended after receiving the hemorrhagic fever vaccine. The hemorrhagic fever vaccine is clinically used primarily to prevent infection by hemorrhagic fever viruses, and vaccination typically involves a three-dose regimen. The vaccine stimulates the body's immune system to produce corresponding antibodies, thereby preventing hemorrhagic fever virus infection. Alcohol intake may cause adverse reactions or interfere with the vaccine's effectiveness.
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Who should not receive the hemorrhagic fever vaccine?
In general, individuals who should not receive the hemorrhagic fever vaccine include pregnant or lactating women, those with a history of allergies, people with fever, patients with infectious diseases, and individuals with neurological disorders. Pregnant or breastfeeding women should not be vaccinated against hemorrhagic fever, as certain components of the vaccine may affect the growth and development of the fetus or infant.
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What vaccines are administered via subcutaneous injection?
In general, common subcutaneous vaccines mainly include measles-mumps-rubella (MMR) combined vaccine, varicella attenuated live vaccine, zoster attenuated live vaccine, hepatitis A attenuated live vaccine, and epidemic hemorrhagic fever vaccine. Before vaccination, you should truthfully inform the doctor of your health status; after vaccination, follow medical advice for proper care, and seek immediate medical attention if severe discomfort occurs.
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Do I need a vaccine if bitten by a hamster?
Although the likelihood of hamsters carrying the rabies virus is low, they may carry other pathogens such as hantavirus and Clostridium tetani. These pathogens can enter the human body through wounds and cause diseases. In such cases, in addition to thoroughly cleaning and disinfecting the wound, it is also necessary to consider receiving tetanus antitoxin, tetanus immunoglobulin, or hemorrhagic fever vaccine according to a doctor's advice.
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Is it necessary to get the hemorrhagic fever vaccine?
Hemorrhagic fever vaccine is not a mandatory Category I vaccine as defined by the state, and vaccination is not required for everyone. Individuals can decide whether or not to get vaccinated based on their personal circumstances. In China, epidemic hemorrhagic fever is primarily transmitted through rodents. Therefore, vaccination against hemorrhagic fever is highly recommended for individuals who frequently come into contact with natural environments, especially those in endemic areas.
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