The local anesthetic effect has not worn off after 48 hours.

May 16, 2023 Source: Cainiu Health
Dr. Yang Shuwen
Introduction
Local anesthetics usually have a short duration of action and generally wear off gradually within a few hours. If the effects of a local anesthetic persist for as long as 48 hours, it may be due to factors such as excessive dosage, injection site issues, or problems with drug metabolism. In such cases, prompt medical attention is necessary to determine the specific cause and receive appropriate treatment based on the condition and the doctor's recommendations.

In general, if the effects of a local anesthetic have not worn off after 48 hours, it may be due to factors such as excessive dosage, injection site issues, or problems with drug metabolism. A detailed analysis is as follows:

1. Excessive dosage

If the dose of local anesthetic is too high, it may cause prolonged anesthesia and even adverse reactions affecting the nervous and cardiovascular systems. An excessive dose may result in the anesthetic remaining in the body for an extended period, thereby prolonging the duration of its effect.

2. Injection site issues

Local anesthetics may remain at the injection site for a prolonged time, especially if there is inflammation or infection present. In such cases, the anesthetic may be difficult to break down and metabolize, leading to a longer-lasting anesthetic effect.

3. Drug metabolism issues

The rate of metabolism and elimination of local anesthetics varies among individuals. If a person has poor metabolic function, the anesthetic may remain in the body longer, thus extending the duration of anesthesia.

Besides the above factors, prolonged anesthesia may also be caused by individual hypersensitivity or nerve damage. In summary, if the effects of a local anesthetic persist beyond 48 hours, prompt medical evaluation is necessary to determine the underlying cause and receive appropriate treatment based on the condition and physician's recommendations. Additionally, when receiving local anesthesia, it is essential to strictly follow the doctor’s instructions and dosage guidelines to avoid unnecessary risks and complications.


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