What does it mean if the hepatitis B surface antigen level is low, and what should be done?

May 30, 2023 Source: Cainiu Health
Dr. Jiang Weimin
Introduction
In general, a low level of hepatitis B surface antigen may be caused by hepatitis B vaccination, which does not require special treatment, or it may result from hepatitis B virus infection, which requires medication. It is important to note that individuals with low hepatitis B surface antigen levels should actively undergo liver function tests and seek timely medical attention if any discomfort occurs.

Generally, a low level of hepatitis B surface antigen may be caused by hepatitis B vaccination, which does not require special treatment, or it may result from hepatitis B virus infection, which requires medication. The specific details are as follows:

1. Hepatitis B Vaccination

The hepatitis B vaccine is used to prevent hepatitis B infection and has a good preventive effect. During the initial phase after vaccination, a low level of hepatitis B surface antigen may commonly occur. This is usually a normal phenomenon without significant clinical implications, and only careful observation is needed.

2. Hepatitis B Virus Infection

In the early stage of hepatitis B virus infection or after antiviral treatment, patients may also show low levels of hepatitis B surface antigen. However, this does not mean the virus has been eliminated. Long-term follow-up and continued treatment are still necessary. Patients are generally advised to continue taking antiviral medications such as lamivudine tablets or entecavir tablets under the guidance of a physician to promote viral clearance.

It is important to note that patients with low hepatitis B surface antigen levels should actively undergo liver function tests, seek timely medical care if any discomfort occurs, maintain a light diet, and ensure adequate rest in daily life.


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